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Other Pragmatic Trials Resources

Resource Subject Areas Key

Education & Training
Funding Resources
Methods & Theory
Applications & Tools
Publications
Videos
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Lecture Slides & Videos

The Importance of Pragmatic Clinical Trials

Russell Glasgow, PhD
 Video

At the pragmatic trials workshop, Russell Glasgow gives an introductory presentation on the importance of pragmatic clinical trials.

Implementation Science: Methods, Models, and Opportunities to Integrate Evidence, Policy, and Practice​

Russell Glasgow, PhD
 Video

The real-world use of PRECIS-2 domains is explained by Russell Glasgow at the 2014 workshop.

Boot Camp Translation for Patient-centered Outcomes

Elaine Morrato, DrPH, MPH, CPH
 Video

An introduction to Stakeholder Engagement from the CRISP Pragmatic Trials Workshop September 15, 2014

An Overview on Engament

Kim Bailey, PCORI Engagement Officer
 Video

An Overview on Stakeholder Engagement, from PCORI engagement officer Kim Bailey at the 2014 CRISP Pragmatic Trials Workshop.

Study Population & Setting (CRISP) Pragmatic Trials Workshop September 15, 2014

Borsika Rabin, PhD, MPH, PharmD
 Video

Borsika Rabin, Reviews the PRECIS-2 domains from this section in population and setting.

Study Population and Setting - CRISP Pragmatic Trials Workshop 

Elaine Belansky, PhD
 Video

Elaine Belansky discusses applications of study pupulation and setting.

Research Design: A Case Study for Patient-Centered PCT's

C. Daniel Mullins, PhD
 Video

Daniel Mullins discusses the importance of patient-centerdness in PCT research design at the 2014 CRISP Pragmatic Trials workshop

Research Design: An Example of Pragmatic Trials applied

P. Michael Ho, MD, PhD
 Video

Mike Ho presents an example of pragmatic trial study design: clopidogrel treatment

Statistical Considerations

L. Miriam Dickinson, PhD
 Video

Key lessons learned in encountering statistical considerations in the field, presented by Miriam Dickinson.

Real-world Use: Video playlist

Russell Glasgow, PhD, William R. Hiatt, MD, Jerry Krishnan, MD, PhD
 Video 1

Russell Glasgow reviews concepts addressed in this section and introduces some of the key issues related to real-world use of pragmatic trials.

 Video 2
Jerry Krishnan discusses real-world use of pragmatic trials, sharing the results of a study and comparing trial designs.
 Video 3
Will Hiatt highlights the challenges to pragmatic trials in use and meaningful interpretation of results.

Centers & Networks

Center for Research in Implementation Science and Prevention (CRISP)

CRISP is one of three national centers funded by the Agency for Healthcare Research and Quality (AHRQ) that focuses on improving clinical preventive services within primary care practice. CRISP brings together expertise in implementation of preventive services, practice-based research networks (PBRNs) and national authorities in innovative health information technology (HIT). The website contains archived D&I webinars, educational opportunities, research information. Toolkits are coming soon.

PCORnet: the National Patient-Centered Clinical Research Network

PCORnet, the National Patient-Centered Clinical Research Network, will transform clinical research by engaging patients, care providers, and health systems in collaborative partnerships to improve healthcare and advance medical knowledge. By bringing research and patient care together, this innovative health data network will be able to explore the questions that matter most to patients and their families..

CCTSI

The CCTSI is a collaborative enterprise between University of Colorado Denver Anschutz Medical Campus, University of Colorado Boulder, Colorado State University, six affiliated Hospitals and health care organizations, and multiple community organizations with a goal to accelerate the translation of research discoveries into improved patient care and public health. This website is the CCTSI’s portal for communication and collaboration tools. It is designed to help you navigate the many valuable clinical and translational research and educational resources available through the CCTSI.

IMPLEMENTATION NETWORK

This listserv distributes information on late-breaking research, practice, and policy activities in health care and public health, including publications, reports, conferences, meetings, program announcements, funding opportunities, and other various proceedings. The listserv encompasses the areas including: scale-up/spread, capacity building, knowledge translation, quality improvement, research-to-practice, diffusion, knowledge transfer and exchange, adoption, complex interventions, implementation strategies, action research, translational research, and other related terms and sub-disciplines. It is supported in part by VA QUERI. This website is managed by Wynne Norton, Ph.D at the University of Alabama at Birmingham, School of Public Health.

Make Research Matter (MRM)

MRM provides tools for researchers to incorporate pragmatic trial design into their products. The MRM site contains four main tools: Planning Tools, Resource Library, Narrative Library, and Glossary.

QUERI Program

QUERI focuses on the quality of healthcare for Veterans. QUERI seeks to improve care using research evidence to improve clinical practice. QUERI’s Resource Center, the Center for Implementation Practice and Research Support (CIPRS) provides tools, resources for theories, methods, models, frameworks, journals, news, among many other resources for those interested in implementation science research.

Funding Agencies

Agency for Healthcare Research and Quality (AHRQ)

The AHRQ site contains a variety of resources for patients and consumers, healthcare professionals, policy makers, and researchers. AHRQ offers toolkits, funding opportunities, and other information on patient education, preventive care, quality, and patient safety.

NIH/National Cancer Institute: Implementation Science

This website is a comprehensive resource for resources and interactive tools, funding opportunities, conferences and trainings, publications, and presentations.

Centers for Disease Control and Prevention (CDC)

The CDC website offers D&I resources in a variety of specific areas including violence protection, chronic disease prevention, tobacco cessation, and cancer control. The website also has extensive information on health communication, social media and marketing.

The Patient-Centered Outcomes Research Institute (PCORI)

CRISP is one of three new national centers funded by the Agency for Healthcare Research and Quality (AHRQ) that focuses on improving clinical preventive services within primary care practice. CRISP brings together expertise in implementation of preventive services, practice-based research networks (PBRNs) and national authorities in innovative health information technology (HIT). The website contains archived D&I webinars, educational opportunities, research information. Toolkits are coming soon.

Journals & Books

Clinical and Translational Science

CRISP is one of three new national centers funded by the Agency for Healthcare Research and Quality (AHRQ) that focuses on improving clinical preventive services within primary care practice. CRISP brings together expertise in implementation of preventive services, practice-based research networks (PBRNs) and national authorities in innovative health information technology (HIT). The website contains archived D&I webinars, videos from pragmatic trials conferences, educational opportunities and research information. More Toolkits are coming soon.

Duke's Pragmatic Trials Living Textbook

Designed by the NIH Collaboratory to provide a complete suite of information on how to understand, design, conduct, analyze & disseminate pragmatic clinical trials (PCTs).

Implementation Science

This website is an open access, peer-reviewed online journal that aims to publish research relevant to the scientific study of methods to promote the uptake of research findings into routine healthcare in clinical, organisational or policy contexts.

Websites

PRECIS-2

Developed by the Health Informatics Centre (University of Dundee) 2005, this website is not only a great resource for pragmatic trial design, but a database of registered trials. Designing clinical trials is challenging. PRECIS – PRagmatic Explanatory Continuum Indicator Summaries – is a clever acronym for a tool to help trialists designing clinical trials consider where they would like their trial to be on the pragmatic/explanatory continuum.

National Clinical & Translational Science Awards (CTSA)

The Clinical and Translational Science Awards (CTSA) program, supported by the National institutes of Health, is comprised of about 60 academic medical institutions and a coordinating center all working together to transform the way biomedical research is conducted. Its goals are to accelerate the translation of laboratory discoveries into treatments for patients, to engage communities in clinical research efforts, and to train a new generation of clinical and translational researchers. The website contains tools, best practices, collaboration opportunities, and other resources.

RE-AIM

The RE-AIM framework is designed to enhance the quality, speed, and public health impact of efforts to translate research into practice in five steps. This site provides an explanation of and resources for those wanting to apply the RE-AIM framework. Among the RE-AIM website features are Tools and resources to facilitate implementation, and a comprehensive list of RE-AIM publications and presentations organized alphabetically by year.

Precede-Proceed

This website offers information on the Precede-Proceed model and links to other resources such as conferences, journals, career opportunities, and information on organizations and health policy.

Training Programs

Online Course: Pragmatic Randomized Controlled Trials in Health Care

The goals of this course are to understand the consequences of designing the wrong kinds of trials, and how best to design pragmatic randomized trials for patients and decision makers in the real world contexts. The course also examines how these can be combined with economic evaluations and qualitative research – to answer important questions about how much these interventions cost, and how they are experienced by the recipients.

- This Course Cycle began in February 2015, but please check back in the future for online course schedules. 

Training Institute for Dissemination and Implementation Research in Health (TIDIRH)

  Watch The Video

The Office of Behavioral and Social Sciences Research, National Institutes of Health, in partnership with the National Cancer Institute, the National Institute of Mental Health, and the U.S. Department of Veterans Affairs, is sponsoring this 5-day training institute to provide participants with a thorough grounding in conducting dissemination and implementation research in health.

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